The Cyr61 Is a Potential Target for Rotundifuran, a Natural Labdane-Type Diterpene from Vitex trifolia L., to Trigger Apoptosis of Cervical Cancer Cells
نویسندگان
چکیده
منابع مشابه
Labdane-type diterpenoids from the fruits of Vitex trifolia.
Seven new labdane-type diterpenoids, vitextrifolins A-G (1-7), along with eight previously reported analogues, were isolated from the fruits of Vitex trifolia. The structures of 1-7 were elucidated by spectroscopic data interpretation. The isolates were evaluated for their cytotoxicity against four human cancer cell lines (A549, HCT116, HL-60, and ZR-75-30), but all were inactive (IC(50) < 5 μg...
متن کاملA new labdane diterpene from Vitex negundo.
CONTEXT Vitex negundo Linn. (Verbenaceae) seeds are pepper substitute and occasionally used as a condiment for edible purposes. The seeds also find use for analgesia, sedation, rheumatism and joint inflammation in folk medicine. OBJECTIVE To isolate and characterize bioactive constituents from V. negundo seeds. MATERIALS AND METHODS The ethanol extract of V. negundo seeds was subjected to r...
متن کاملfrom linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar
chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...
15 صفحه اولCytotoxic terpenoids from the fruits of Vitex trifolia L.
Two new labdane-type diterpenoids vitetrifolin H (1) and vitetrifolin I (2), and one new monoterpenoid vitexoid (3), were isolated from the fruits of Vitex trifolia L., together with seven known diterpenoids. Structures of all compounds were elucidated by extensive spectroscopic methods. All these compounds exhibited inhibition of Hela cell proliferation, with IC50 values in the range of 4-28 m...
متن کاملANTIMICROBIAL POTENTIAL OF VITEX TRIFOLIA Linn
Vitex trifolia (Local name - Nirnocchi, sirunocchi) is well known for its medicinal property. The present investigation encompasses evaluation of antibacterial potential of Vitex trifolia against certain pathogenic bacterial strains. Preliminary phytochemical studies were also made and results are given.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2021
ISSN: 1942-0994,1942-0900
DOI: 10.1155/2021/6677687